An alkaloid with diverse biological activities; inhibits AChE (IC50 = 15 μM); nematocidal against S. ratti and S. venezuelensis third instar larvae (PC50s = 18 and 30 μM

Corydaline – 50 mg

Brand:
Cayman
CAS:
518-69-4
Storage:
-20
UN-No:
Non-Hazardous - /

Corydaline is an alkaloid that has been found in C. cava and has diverse biological activities.{45597,45598,45599,45600} It inhibits acetylcholinesterase (AChE; IC50 = 15 μM).{45597} Corydaline is nematocidal against S. ratti and S. venezuelensis third instar larvae with 50% paralysis (PC50) values of 18 and 30 μM, respectively.{45598} It inhibits thrombin-induced platelet aggregation in vitro (IC50 = 54.16 μg/ml).{45599} Corydaline (1 and 3 mg/kg) increases gastric emptying in rat models of apomorphine- and laparotomy-induced delayed gastric emptying.{45600}  

 

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SKU: 27654 - 50 mg Category:

Description

An alkaloid with diverse biological activities; inhibits AChE (IC50 = 15 μM); nematocidal against S. ratti and S. venezuelensis third instar larvae (PC50s = 18 and 30 μM, respectively); inhibits thrombin-induced platelet aggregation in vitro (IC50 = 54.16 μg/ml); increases gastric emptying in rat models of apomorphine- and laparotomy-induced delayed gastric emptying at 1 and 3 mg/kg

Formal name: 5,8,13S,13aR-tetrahydro-2,3,9,10-tetramethoxy-13-methyl-6H-dibenzo[a,g]quinolizine

Synonyms:  (+)-Corydaline|D-Corydaline|NSC 406036

Molecular weight: 369.5

CAS: 518-69-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Alkaloids||Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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