A pteridine with antioxidant activities; scavenges DPPH radicals in a cell-free assay at 20-100 µM; inhibits copper ion-induced oxidation of LDL in a cell-free assay and decreases TBARS produced by THP-1 cells cultured with LDL at 2-10 µM; inhibits necrosis induced by oxLDL in U937

7,8-Dihydroneopterin – 10 mg

Brand:
Cayman
CAS:
1218-98-0
Storage:
-20
UN-No:
Non-Hazardous - /

7,8-Dihydroneopterin is a pteridine with antioxidant activities.{47629} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay when used at concentrations ranging from 20 to 100 µM. 7,8-Dihydroneopterin (2-10 µM) inhibits copper ion-induced oxidation of LDL in a cell-free assay and decreases thiobarbituric acid reactive substances (TBARS) produced by THP-1 cells cultured with LDL.{47630,47631} It inhibits necrosis induced by oxidized LDL (oxLDL) in U937, but not THP-1, cells when used at a concentration of 200 µM.{47632}  

 

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SKU: 27606 - 10 mg Category:

Description

A pteridine with antioxidant activities; scavenges DPPH radicals in a cell-free assay at 20-100 µM; inhibits copper ion-induced oxidation of LDL in a cell-free assay and decreases TBARS produced by THP-1 cells cultured with LDL at 2-10 µM; inhibits necrosis induced by oxLDL in U937, but not THP-1, cells at 200 µM

Formal name: 2-amino-7,8-dihydro-6-[(1S,2R)-1,2,3-trihydroxypropyl]-4(3H)-pteridinone

Synonyms:  D-erythro-7,8-Dihydroneopterin

Molecular weight: 255.2

CAS: 1218-98-0

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cell Biology|Cell Death|Necrosis||Research Area|Immunology & Inflammation|Innate Immunity

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