A JAK1 inhibitor; >20- and >200-fold selective for JAK1 over JAK2 and JAK3

Itacitinib – 1 mg

Brand:
Cayman
CAS:
1334298-90-6
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Itacitinib is an inhibitor of JAK1.{36733} It is greater than 20- and 200-fold selective for JAK1 over JAK2 and JAK3, respectively.  

 

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SKU: 27597 - 1 mg Category:

Description

A JAK1 inhibitor; >20- and >200-fold selective for JAK1 over JAK2 and JAK3, respectively

Formal name: 1-[1-[[3-fluoro-2-(trifluoromethyl)-4-pyridinyl]carbonyl]-4-piperidinyl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile

Synonyms:  INCB 039110

Molecular weight: 553.5

CAS: 1334298-90-6

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Kinase Inhibitors|JAK Family||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling

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