A meroterpenoid fungal metabolite; has insecticidal activity against third instar silkworm larvae (LD50 = 10 μg/g of diet); selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human α1β2γ2 subunit-containing GABA receptors (IC50 = 1.48 μM)

Chrodrimanin B – 1 mg

Brand:
Cayman
CAS:
132196-54-4
Storage:
-20
UN-No:
Non-Hazardous - /

Chrodrimanin B is a meroterpenoid fungal metabolite that has been found in Talaromyces species.{48232} It has insecticidal activity against third instar silkworm larvae (LD50 = 10 μg/g of diet). Chrodrimanin B selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human α1β2γ2 subunit-containing GABA receptors (IC50 = 1.48 μM).{48233} The structure of thailandolide B, originally described as a C-9 epimer of chrodrimanin B, was revised in 2012 and is identical to that of chrodrimanin B.{48232}  

 

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SKU: 27585 - 1 mg Category:

Description

A meroterpenoid fungal metabolite; has insecticidal activity against third instar silkworm larvae (LD50 = 10 μg/g of diet); selectively inhibits the silkworm GABA receptor RDL (IC50 = 1.13 nM) over human α1β2γ2 subunit-containing GABA receptors (IC50 = 1.48 μM)

Formal name: (1R,2R,7aR,8S,9aR,13aS,13bS)-1-(acetyloxy)-1,8,9,9a,10,13a,13b,14-octahydro-5,8-dihydroxy-2,7a,10,10,13a-pentamethyl-2H,4H-benzo[a]pyrano[3,4-j]xanthene-4,11(7aH)-dione

Synonyms:  Thailandolide B

Molecular weight: 484.5

CAS: 132196-54-4

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Pesticides|Insecticides||Research Area|Toxicology|Environmental|Agriculture

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