A colorimetric plasma kallikrein substrate; cleavage of the PFR peptide sequence releases pNA

D-Pro-Phe-Arg-pNA (hydrochloride) – 250 mg

Brand:
Cayman
CAS:
62354-56-7
Storage:
-20
UN-No:
Non-Hazardous - /

D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein.{48597} Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.  

 

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SKU: 27569 - 250 mg Category:

Description

A colorimetric plasma kallikrein substrate; cleavage of the PFR peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity

Formal name: D-prolyl-L-phenylalanyl-N-(4-nitrophenyl)-L-argininamide, dihydrochloride

Synonyms:  D-Pro-Phe-Arg-p-nitroaniline|pFR-pNA|Plasma Kallikrein Chromogenic Substrate

Molecular weight: 611.5

CAS: 62354-56-7

Purity: ≥95%

Formulation: A crystalline solid

Application|Enzyme Activity||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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