A phenolic ketone that has diverse biological activities

6-Paradol – 250 mg

Brand:
Cayman
CAS:
27113-22-0
Storage:
-20
UN-No:
Non-Hazardous - /

6-Paradol is a phenolic ketone that has been found in ginger (Z. officinale) and has diverse biological activities, including antioxidant, anti-inflammatory, and anti-hyperglycemic properties.{50301,50302,50303} It inhibits hydrogen peroxide-induced oxidation of cell-free calf thymus DNA when used at a concentration of 100 μM.{50301} In vitro, 6-paradol (10 μg/ml) inhibits LPS-induced nitric oxide (NO), IL-6, and TNF-α production by mouse BV-2 microglia.{50302} In vivo, 6-paradol (6.75 mg/kg per day) lowers blood glucose levels in an oral glucose tolerance test (OGTT) and inhibits weight-gain in a mouse model of high-fat diet-induced obesity.{50303}  

 

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SKU: 27554 - 250 mg Category:

Description

A phenolic ketone that has diverse biological activities, including antioxidant, anti-inflammatory, and anti-hyperglycemic properties; inhibits hydrogen peroxide-induced oxidation of cell-free calf thymus DNA at 100 μM; inhibits LPS-induced NO, IL-6, and TNF-α production by mouse BV-2 microglia at 10 μg/ml; lowers blood glucose levels in an OGTT and inhibits weight-gain in a mouse model of high-fat diet-induced obesity at 6.75 mg/kg per day

Formal name: 1-(4-hydroxy-3-methoxyphenyl)-3-decanone

Synonyms: 

Molecular weight: 278.4

CAS: 27113-22-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Polyphenols||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|DNA/RNA Oxidative Damage

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