A fungal metabolite with diverse biological activities; active against L. braziliensis at 0.15 µg/ml; active against B. xylophilus at 100 µg/ml; inhibits proliferation of NCI-H460

Bikaverin – 5 mg

Brand:
Cayman
CAS:
33390-21-5
Storage:
-20
UN-No:
- 2811 / 6.1

Bikaverin is a fungal metabolite originally isolated from F. oxysporum f. sp. lycopersici that has diverse biological activities, including antiprotozoal, nematocidal, antiproliferative, and fungicidal properties.{46194,46195,46196,46197} It is active against L. braziliensis when used at a concentration of 0.15 µg/ml and against B. xylophilus at a concentration of 100 µg/ml.{46195} It inhibits proliferation of NCI-H460, MIA PaCa-2, MCF-7, and SF-268 cells (IC50s = 0.43, 0.26, 0.42, and 0.38 µM, respectively).{46196} Bikaverin inhibits the growth of certain plant pathogenic fungi, including R. solani, P. capsici, P. infestans, and M. grisea (IC50s = P. infestans and P. recondita, respectively, when applied at a concentration of 300 µg/ml.  

 

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SKU: 27467 - 5 mg Category:

Description

A fungal metabolite with diverse biological activities; active against L. braziliensis at 0.15 µg/ml; active against B. xylophilus at 100 µg/ml; inhibits proliferation of NCI-H460, MIA PaCa-2, MCF-7, and SF-268 cells (IC50s = 0.43, 0.26, 0.42, and 0.38 µM, respectively); inhibits the growth of certain plant pathogenic fungi, including R. solani, P. capsici, P. infestans, and M. grisea (IC50s = <1.2, 10, 60, and 70 µg/ml, respectively); inhibits the development and provides disease control of tomato late blight and wheat leaf rust at 300 µg/ml

Formal name: 6,11-dihydroxy-3,8-dimethoxy-1-methyl-10H-benzo[b]xanthene-7,10,12-trione

Synonyms:  ,Lycopersin|NSC 215139

Molecular weight: 382.3

CAS: 33390-21-5

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Pesticides|Fungicides||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Leishmaniasis||Research Area|Toxicology|Environmental|Agriculture

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