An anthraquinone with diverse biological activities; active against Gram-positive bacteria

Bostrycin – 500 µg

Brand:
Cayman
CAS:
21879-81-2
Storage:
-20
UN-No:
Non-Hazardous - /

Bostrycin is an anthraquinone originally isolated from B. alpestre that has diverse biological activities, including antibacterial, antiproliferative, and phytotoxic properties.{47270,47271} It is active against Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), M. tuberculosis, and C. botulinum.{47271} Bostrycin inhibits proliferation of A549 lung adenocarcinoma cells when used at concentrations ranging from 10 to 30 µM, as well as halts the cell cycle at the G0/G1 phase and induces apoptosis in A549 cells.{47272} It is a phytotoxin that induces necrosis of water hyacinth leaves when used at a concentration of approximately 7 µg/ml.{47273} Bostrycin has been used as a cross-linking agent for protein immobilization that retains bacteriostatic activity when immobilized on nonwoven polypropylene fabric.{47271}  

 

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SKU: 27466 - 500 µg Category:

Description

An anthraquinone with diverse biological activities; active against Gram-positive bacteria, including MRSA, M. tuberculosis, and C. botulinum; inhibits proliferation of A549 lung adenocarcinoma cells at 10-30 µM; a phytotoxin that induces necrosis of water hyacinth leaves at ~7 µg/ml; has been used as a cross-linking agent for protein immobilization that retains bacteriostatic activity when immobilized on nonwoven polypropylene fabric

Formal name: (5S,6R,7S)-5,6,7,8-tetrahydro-5,6,7,9,10-pentahydroxy-2-methoxy-7-methyl-1,4-anthracenedione

Synonyms:  Rhodosporin

Molecular weight: 336.3

CAS: 21879-81-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Anthraquinones||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|MRSA||Research Area|Infectious Disease|Bacterial Diseases|Tuberculosis||Research Area|Plant Biology|Phytotoxins

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