A fungal metabolite; increases NF-κB activity at 60-130 µg/ml; enhances LPS-induced TNF-α secretion and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells

Streptazolin – 1 mg

Brand:
Cayman
CAS:
80152-07-4
Storage:
-20
UN-No:
Non-Hazardous - /

Streptazolin is a fungal metabolite originally isolated from S. viridochromogenes.{49059} It increases NF-κB activity when used at concentrations ranging from 60 to 130 µg/ml, at least in part, via PI3K signaling.{49060} Streptazolin enhances TNF-α secretion induced by LPS and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells.  

 

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SKU: 27266 - 1 mg Category:

Description

A fungal metabolite; increases NF-κB activity at 60-130 µg/ml; enhances LPS-induced TNF-α secretion and enhances IL-8 secretion when used alone or in combination with LPS in THP-1 Blue cells

Formal name: 4-ethylidene-2aS,3S,4Z,6,7,7bS-hexahydro-3-hydroxy-1H-2-oxa-7a-azacyclopent[cd]inden-1-one

Synonyms:  (+)-Streptazolin

Molecular weight: 207.2

CAS: 80152-07-4

Purity: ≥70%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation

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