Description
A uPA inhibitor (Ki = 10 nM); 4,000- and 2,700-fold selective for uPA over tPA and plasmin, respectively; inhibits exogenous uPA in human chronic wound fluid (IC50 = 0.89 μM); topical administration inhibits exogenous uPA activity in a porcine excisional wound model
Formal name: N-[[1-[(aminoiminomethyl)amino]-4-chloro-7-isoquinolinyl]sulfonyl]-2-methyl-alanine
Synonyms:
Molecular weight: 385.8
CAS: 256477-09-5
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases
