A form of vitamin E with antioxidant and anti-inflammatory properties; traps and detoxifies reactive nitrogen oxide species

(±)-γ-Tocopherol – 25 mg

Brand:
Cayman
CAS:
7616-22-0
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties.{15114,15117,8680} It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays.{15114,15117} It also reduces the synthesis of prostaglandin E2 (PGE2; Item No. 14010) induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells (IC50s = 7.5 and 4 μM, respectively).{8680} (±)-γ-Tocopherol (10 μM) inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated with IL-1β. Serum levels of (±)-γ-tocopherol are decreased in patients with cardiovascular disease.{15114} [Matreya, LLC. Catalog No. 1073]  

 

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SKU: 27193 - 25 mg Category:

Description

A form of vitamin E with antioxidant and anti-inflammatory properties; traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays; reduces PGE2 synthesis induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells (IC50s = 7.5 and 4 μM, respectively); inhibits LPS-induced nitrite release and iNOS expression in RAW 264.7 cells at 10 μM and reduces COX-2 activity in A549 cells pretreated with IL-1β; serum levels are decreased in patients with cardiovascular disease

Formal name: 3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol

Synonyms:  7,8-Dimethyltocol|all-rac-γ-Tocopherol|DL-γ-Tocopherol

Molecular weight: 416.7

CAS: 7616-22-0

Purity: ≥95%

Formulation: A solution in hexane

Product Type|Biochemicals|Natural Products|Vitamins||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Research Area|Cardiovascular System|Cardiovascular Diseases||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen

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