A racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide

(R,S)-Carvedilol Glucuronide – 500 µg

Brand:
Cayman
CAS:
114869-83-9
Storage:
-20
UN-No:
Non-Hazardous - /

(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol (Item No. 15418) metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.{45165} (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1 and UGT2B4. (S)-Carvedilol glucuronide is formed via glucuronidation of (S)-carvedilol by UGT2B4 and UGT2B7.  

 

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SKU: 27173 - 500 µg Category:

Description

A racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide

Formal name: 2-(9H-carbazol-4-yloxy)-1-[[[2-(2-methoxyphenoxy)ethyl]amino]methyl]ethyl β-D-glucopyranosiduronic acid

Synonyms: 

Molecular weight: 582.6

CAS: 114869-83-9

Purity: ≥95% (mixture of diastereomers)

Formulation: A solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Cardiovascular Diseases|Heart Failure||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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