An active metabolite of carvedilol; a β-adrenergic receptor antagonist; formed through oxidation by CYP2D6; inhibits the formation of DPPH radicals in a cell-free assay

4′-hydroxyphenyl Carvedilol – 5 mg

Brand:
Cayman
CAS:
142227-49-4
Storage:
-20
UN-No:
Non-Hazardous - /

4’-hydroxyphenyl Carvedilol is a metabolite of carvedilol (Item No. 15418) that is a more potent β-adrenergic receptor antagonist than carvedilol but has weaker vasodilatory activity.{49062} It is formed through oxidation primarily by the cytochrome P450 (CYP) isoform CYP2D6.{49063} 4’-hydroxyphenyl Carvedilol inhibits the formation of DPPH radicals in a cell-free assay.{49064}  

 

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SKU: 27172 - 5 mg Category:

Description

An active metabolite of carvedilol; a β-adrenergic receptor antagonist; formed through oxidation by CYP2D6; inhibits the formation of DPPH radicals in a cell-free assay

Formal name: 4-[2-[[3-(9H-carbazol-4-yloxy)-2-hydroxypropyl]amino]ethoxy]-3-methoxy-phenol

Synonyms:  BM 140686

Molecular weight: 422.5

CAS: 142227-49-4

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Cardiovascular Diseases|Heart Failure||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Heart|Arrhythmia||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic||Research Area|Toxicology|Drug Metabolism|Cytochrome P450||Research Area|Toxicology|Drug Metabolism|Drug Metabolites

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