An SCD inhibitor (IC50 = 6.1 nM in HepG2 cells); dose-dependently reduces levels of palmitoleic acid and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet; reduces hepatic triglyceride levels in sucrose-fed rats at 20 mg/kg

CVT-12012 – 10 mg

Brand:
Cayman
CAS:
1018675-35-8
Storage:
-20
UN-No:
Non-Hazardous - /

CVT-12012 is an orally bioavailable inhibitor of stearoyl-CoA desaturase (SCD; IC50 = 6.1 nM in HepG2 cells).{46204} It dose-dependently reduces levels of the SCD desaturation products palmitoleic acid (Item No. 10009871) and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet. CVT-12012 (20 mg/kg) also reduces hepatic triglyceride levels in sucrose-fed rats.  

 

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SKU: 27156 - 10 mg Category:

Description

An SCD inhibitor (IC50 = 6.1 nM in HepG2 cells); dose-dependently reduces levels of palmitoleic acid and vaccenic acid in the plasma and liver of rats fed a high-sucrose diet; reduces hepatic triglyceride levels in sucrose-fed rats at 20 mg/kg

Formal name: 2-hydroxy-N-[2-[3-methyl-2-oxo-7-[[[3-(trifluoromethyl)phenyl]methyl]amino]-1(2H)-quinoxalinyl]ethyl]-acetamide

Synonyms: 

Molecular weight: 434.4

CAS: 1018675-35-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias

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