Description
A fluorogenic substrate for caspase-8 and granzyme B; AFC is released upon enzymatic cleavage by caspase-8 or granzyme B and its fluorescence can be used to quantify caspase-8 or granzyme B activity; ex/em = 380/500 nm, respectively
Formal name: N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine
Synonyms: Z-Ile-Glu-Thr-Asp-7-amino-4-Trifluormethylcoumarin
Molecular weight: 821.8
CAS: 219138-02-0
Purity: ≥90%
Formulation: A solid
Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases
