A form of GHK containing palmitic acid; penetrates the stratum corneum to the epidermal and dermal skin layers; increases collagen synthesis in human skin fibroblasts in vitro at 0.5 µM; reduces collagen degradation ex vivo in patient-derived human skin samples irradiated with UVA light at 6 ppm; has been used with C12DMAO to study self-assembly of the mixture into aggregates

Pal-GHK – 1 g

Brand:
Cayman
CAS:
147732-56-7
Storage:
-20
UN-No:
Non-Hazardous - /

Pal-GHK is a form of the extracellular matrix-derived peptide GHK (Item No. 27168) containing palmitic acid (Item No. 10006627), which allows it to penetrate the stratum corneum to the epidermal and dermal skin layers.{42842} Pal-GHK (0.5 µM) increases collagen synthesis in human skin fibroblasts in vitro. It reduces collagen degradation ex vivo in patient-derived human skin samples irradiated with UVA light when used at a concentration of 6 ppm. It has been used with the zwitterionic surfactant C12 dodecyldimethylamine oxide (C12DMAO) to study self-assembly of the mixture into aggregates, ribbons, and nanobelts.{42843,42844} Pal-GHK has also been used as an internal standard for the quantification of pal-KTTKS in anti-wrinkle creams by LC-MS/MS.{42845}  

 

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SKU: 27059 - 1 g Category:

Description

A form of GHK containing palmitic acid; penetrates the stratum corneum to the epidermal and dermal skin layers; increases collagen synthesis in human skin fibroblasts in vitro at 0.5 µM; reduces collagen degradation ex vivo in patient-derived human skin samples irradiated with UVA light at 6 ppm; has been used with C12DMAO to study self-assembly of the mixture into aggregates, ribbons, and nanobelts; has been used as an internal standard for the quantification of pal-KTTKS in anti-wrinkle creams by LC-MS/MS

Formal name: N-(1-oxohexadecyl)glycyl-L-histidyl-L-lysine

Synonyms:  C16-GHK|C16-GK-3|Palmitoyl Oligopeptide|Palmitoyl Tripeptide-1

Molecular weight: 578.8

CAS: 147732-56-7

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Peptides||Research Area|Cell Biology|ECM & Adhesion Molecules

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