A glycoside isoflavone; inhibits LPS-induced production of nitrite

Ononin – 10 mg

Brand:
Cayman
CAS:
486-62-4
Storage:
-20
UN-No:
Non-Hazardous - /

Ononin is a glycoside isoflavone that has been found in soybeans and A. mongholicus and has anti-inflammatory and neuroprotective activities.{42797,42798,42799} Ononin (5 µM) inhibits LPS-induced production of nitrite, prostaglandin E2 (PGE2; Item No. 14010), and the pro-inflammatory cytokines IL-1β, IL-6, and TNF-α by RAW 264.7 macrophages.{42799} It also inhibits glutamate-induced toxicity in rat adrenal PC12 cells when used at a concentration of 0.025 µg/ml.{42798}  

 

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SKU: 27046 - 10 mg Category:

Description

A glycoside isoflavone; inhibits LPS-induced production of nitrite, PGE2, and the pro-inflammatory cytokines IL-1β, IL-6, and TNF-α by RAW 264.7 macrophages at 5 µM; inhibits glutamate-induced toxicity in rat adrenal PC12 cells at 0.025 µg/ml

Formal name: 7-(β-D-glucopyranosyloxy)-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one

Synonyms:  Formononetin 7-O-Glucoside|Formononetin 7-O-β-D-Glucopyranoside|Formononetin Glucoside

Molecular weight: 430.4

CAS: 486-62-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Glycosides||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Neuroprotection

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