Taurine – 100 g

Brand:
Cayman
CAS:
107-35-7
Storage:
-20
UN-No:
Non-Hazardous - /

Taurine is a sulfur-containing amino acid produced endogenously and also ingested in the diet.{43869} It is ubiquitously present in most cells and has diverse biological activities, including antioxidative, anticancer, cardioprotective, and neuroprotective properties.{43869,43870,43871,14507} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals when used at concentrations ranging from 125 to 1,000 µg/ml and decreases the viability of MCF-7 and MDA-MB-231 human breast cancer cells.{43870} It prevents left ventricular function dysfunction in the mdx mouse model of late-stage Duchenne muscular dystrophy when administered at a dose of 1 g/kg per day for six months.{43871} Taurine (100 µM) prevents neurotoxicity induced by amyloid-β (Aβ) or the glutamate receptor agonists glutamate, NMDA (Item No. 14581), or kainic acid (Item No. 78050) in chick embryonic retinal neurons, an effect that can be blocked by the GABAA receptor antagonist picrotoxin (Item No. 20771).{14507}  

 

Available on backorder

SKU: 27031 - 100 g Category:

Description

A sulfur-containing amino acid; scavenges DPPH radicals at 125-1,000 µg/ml; decreases the viability of MCF-7 and MDA-MB-231 human breast cancer cells; prevents left ventricular function dysfunction in the mdx mouse model of late-stage Duchenne muscular dystrophy at 1 g/kg per day for six months; prevents neurotoxicity induced by Aβ, NMDA, or kainic acid in chick embryonic retinal neurons


Formal name: 2-amino-ethanesulfonic acid

Synonyms:  NSC 32428|β-Aminoethylsulfonic Acid

Molecular weight: 125.1

CAS: 107-35-7

Purity: ≥95%

Formulation: A crystalline solid


Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Death||Research Area|Cardiovascular System|Heart||Research Area|Neuroscience|Neuroprotection||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic