An agonist of S. hermonthica ShHTL7; binds to ShHTL7 (IC50 = 0.31 µM) over ShHTL2-6

Sphynolactone-7 – 1 mg

Brand:
Cayman
CAS:
2305752-57-0
Storage:
-20
UN-No:
Non-Hazardous - /

Sphynolactone-7 (SPL7) is an agonist of Striga hyposensitive to light receptor 7 (ShHTL7), which is found in the parasitic plant S. hermonthica.{35472} It selectively binds to ShHTL7 (IC50 = 0.31 µM) over ShHTL2-6, ShHTL9-10, and the strigolactone receptor AtD14 at 10 µM but does inhibit ShHTL8 and ShHTL11 (IC50s = 1.2 and 7.8 µM, respectively). SPL7 induces S. hermonthica seed germination in the absence of a host, which is fatal to this obligate parasite, with a minimum effective concentration of 10 fM. It induces suicidal germination of S. hermonthica seeds and decreases the number of plants emerging from the soil, as well as reduces S. hermonthica-induced senescence in maize plants when pre-applied to the soil of co-cultivated maize plants and S. hermonthica seeds at a concentration of 10 nM.  

 

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Description

An agonist of S. hermonthica ShHTL7; binds to ShHTL7 (IC50 = 0.31 µM) over ShHTL2-6, ShHTL9-1, and the strigolactone receptor AtD14 at 10 µM but does inhibit ShHTL8 and ShHTL11 (IC50s = 1.2 and 7.8 µM, respectively); induces fatal S. hermonthica seed germination (MEC = 10 fM); induces suicidal germination of S. hermonthica seeds and decreases the number of plants emerging from the soil, as well as reduces S. hermonthica-induced senescence in maize plants when pre-applied to the soil of co-cultivated maize plants and S. hermonthica seeds at 10 nM

Formal name: 4-[(4-butoxyphenyl)sulfonyl]-1-piperazinecarboxylic acid, 2,5-dihydro-4-methyl-5-oxo-2-furanyl ester

Synonyms:  SPL7​

Molecular weight: 438.5

CAS: 2305752-57-0

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Plant Biology|Plant Growth Regulators

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