A fungal metabolite with diverse biological activities; an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM); an inhibitor of ACAT (IC50 = 22.9 µM); an antagonist of oxytocin receptors (IC50 = 67 µM); inhibits RNA synthesis in P388 murine leukemia cells

Penicillide – 1 mg

Brand:
Cayman
CAS:
55303-92-9
Storage:
-20
UN-No:
Non-Hazardous - /

Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities.{42654,42655,42656,42657,42658} It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM) and acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 22.9 µM).{42655,42656} It is also an antagonist of oxytocin receptors (IC50 = 67 µM).{42657} Penicillide inhibits RNA synthesis in P388 murine leukemia cells.{42658}  

 

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SKU: 26912 - 1 mg Category:

Description

A fungal metabolite with diverse biological activities; an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM); an inhibitor of ACAT (IC50 = 22.9 µM); an antagonist of oxytocin receptors (IC50 = 67 µM); inhibits RNA synthesis in P388 murine leukemia cells

Formal name: 11-hydroxy-3-[(1S)-1-hydroxy-3-methylbutyl]-4-methoxy-9-methyl-5H,7H-dibenzo[b,g][1,5]dioxocin-5-one

Synonyms:  Vermixocin A

Molecular weight: 372.4

CAS: 55303-92-9

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Lipid Biochemistry|Acyl-CoAs||Research Area|Lipid Biochemistry|Sterol Lipids

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