A heteroaryldihydropyrimidine with antiviral activity; inhibits HBV replication in HepG2.2.15 cells (IC50 = 202 nM); reduces viral replication and viral load in a humanized mouse model of HBV infection at 25 mg/kg

(±)-BAY 41-4109 – 50 mg

Brand:
Cayman
CAS:
298708-79-9
Storage:
-20
UN-No:
Non-Hazardous - /

(±)-BAY 41-4109 is a heteroaryldihydropyrimidine with antiviral activity.{46251} It inhibits hepatitis B virus (HBV) replication in HepG2.2.15 cells (IC50 = 202 nM) without affecting cell growth. (±)-BAY 41-4109 (25 mg/kg) reduces viral replication and viral load in a humanized mouse model of HBV infection.  

 

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SKU: 26907 - 50 mg Category:

Description

A heteroaryldihydropyrimidine with antiviral activity; inhibits HBV replication in HepG2.2.15 cells (IC50 = 202 nM); reduces viral replication and viral load in a humanized mouse model of HBV infection at 25 mg/kg

Formal name: 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid, methyl ester

Synonyms: 

Molecular weight: 395.8

CAS: 298708-79-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|Hepatitis

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