A signal-off fluorescent probe for detection of mitochondrial membrane potential disruption; has been used with a variety of cell damage and cell death markers to classify nine stages of cell death using flow cytometry; has been used as a quencher to detect serine phosphorylation and tyrosine dephosphorylation PTMs in QRET and mTR-FRET applications; ex/em = 659/666 nm

DiIC1(5) – 250 mg

Brand:
Cayman
CAS:
36536-22-8
Storage:
-20
UN-No:
Non-Hazardous - /

DiIC1(5) is a signal-off fluorescent probe for the detection of mitochondrial membrane potential disruption.{46228,46229} It accumulates in mitochondria and its fluorescence intensity decreases when the mitochondrial membrane potential is disrupted. DilC1(5) has been used in combination with a variety of cell damage and cell death markers to classify nine stages of cell death using flow cytometry.{46230} It has also been used as a quencher for the detection of serine phosphorylation and tyrosine dephosphorylation post-translational modifications (PTMs) in quenching resonance energy transfer (QRET) and mTR-FRET applications.{46229} It displays excitation/emission maxima of 659/666 nm, respectively.  

 

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SKU: 26861 - 250 mg Category:

Description

A signal-off fluorescent probe for detection of mitochondrial membrane potential disruption; has been used with a variety of cell damage and cell death markers to classify nine stages of cell death using flow cytometry; has been used as a quencher to detect serine phosphorylation and tyrosine dephosphorylation PTMs in QRET and mTR-FRET applications; ex/em = 659/666 nm, respectively

Formal name: 2-[5-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-1,3,3-trimethyl-3H-indolium, monoiodide

Synonyms: 

Molecular weight: 510.5

CAS: 36536-22-8

Purity: ≥98%

Formulation: A crystalline solid

Application|Flow Cytometry||Application|Fluorescence||Application|TR-FRET||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death||Research Area|Cell Biology|Mitochondrial Biology

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