A flavonoid with anti-inflammatory and anxiolytic activities; inhibits LPS-induced nitric oxide production in RAW 264.7 cells from 0.16-10 μM; reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury at 10 mg/kg; increases the number of entries and the time spent in the open arms of the elevated plus maze in rats

Apigenin 7-glucoside – 5 mg

Brand:
Cayman
CAS:
578-74-5
Storage:
-20
UN-No:
Non-Hazardous - /

Apigenin 7-glucoside is a flavonoid with anti-inflammatory and anxiolytic activities.{47248,47249} It inhibits LPS-induced nitric oxide production in RAW 264.7 cells when used at concentrations ranging from 0.16 to 10 μM.{47248} In vivo, apigenin 7-glucoside (10 mg/kg) reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury. It also increases the number of entries and the time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic activity.{47249}  

 

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SKU: 26813 - 5 mg Category:

Description

A flavonoid with anti-inflammatory and anxiolytic activities; inhibits LPS-induced nitric oxide production in RAW 264.7 cells from 0.16-10 μM; reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury at 10 mg/kg; increases the number of entries and the time spent in the open arms of the elevated plus maze in rats

Formal name: 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Synonyms:  7-O-β-D-Glucopyranosylapigenin|Apigenin-7-O-β-D-glucoside|Apigetrin|Cosmosiin|NSC 407303

Molecular weight: 432.4

CAS: 578-74-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety

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