A monoacylglycerol containing oleic acid at the sn-1 position; enhances diffusion of cyclosporin A from the donor compartment of a Franz diffusion cell into the stratum corneum

1-Oleoyl Glycerol – 1 g

Brand:
Cayman
CAS:
111-03-5
Storage:
-20
UN-No:
Non-Hazardous - /

1-Oleoyl glycerol is a monoacylglycerol containing oleic acid (Item No. 90260) at the sn-1 position. 1-Oleoyl glycerol (10%), in a formulation with cyclosporin A (Item No. 12088) in propylene glycol, enhances diffusion of cyclosporin A from the donor compartment of a Franz diffusion cell into the stratum corneum, epidermis, and dermis of porcine ear skin, as well as through the skin to the receptor compartment.{48157} Mixed micellar systems containing 1-oleoyl glycerol and bile salts increase the apparent permeability coefficient (Papp) and absorption rate of amphotericin B (Item No. 11636) in perfused rat intestine in vivo.{48158} Formulations containing 1-oleoyl glycerol have been used as emulsifying agents, food additives, and absorption enhancers.  

 

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SKU: 26793 - 1 g Category:

Description

A monoacylglycerol containing oleic acid at the sn-1 position; enhances diffusion of cyclosporin A from the donor compartment of a Franz diffusion cell into the stratum corneum, epidermis, and dermis of porcine ear skin, as well as through the skin to the receptor compartment in a formulation with cyclosporin A in propylene glycol; mixed micellar systems with bile salts increases the Papp and absorption rate of amphotericin B in perfused rat intestine in vivo

Formal name: 9Z-octadecenoic acid, 2,3-dihydroxypropyl ester

Synonyms:  18:1-MG|1-Monoolein|1-Oleoyl-rac-glycerol|MG(18:1)

Molecular weight: 356.5

CAS: 111-03-5

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Glycerolipids||Research Area|Lipid Biochemistry|Glycerolipids

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