Description
An aminoglycoside antibiotic; active against S. aureus, N. gonorrhoeae, E. coli, P. mirabilis, and P. aeruginosa (MICs = 0.4, 3.1, 0.8, 1.6, and 0.4 µg/ml, respectively) as well as Enterococci, Enterobacter, Citrobacter, and Klebsiella species (MICs = 3.1, 0.4, 0.8, and ≤0.2 µg/ml, respectively); induces nephrotoxicity in rats at 50-150 mg/kg; induces neuromuscular block in isolated diaphragm and soleus muscles in rabbits (ED50s = 18.5 and 62.2 mg/kg, respectively)
Formal name: O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-N1-ethyl-D-streptamine, sulfate (2:5)
Synonyms: Netillin|Netilyn
Molecular weight: 720.8
CAS: 56391-57-2
Purity:
Formulation: A crystalline solid
Product Type|Biochemicals|Antibiotics|Aminoglycosides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|STDs
