An aminoglycoside antibiotic; active against S. aureus

Netilimicin (sulfate) – 10 mg

Brand:
Cayman
CAS:
56391-57-2
Storage:
-20
UN-No:
Non-Hazardous - /

Netilimicin is an aminoglycoside antibiotic.{47386} It is active against S. aureus, N. gonorrhoeae, E. coli, P. mirabilis, and P. aeruginosa (MICs = 0.4, 3.1, 0.8, 1.6, and 0.4 µg/ml, respectively) as well as Enterococci, Enterobacter, Citrobacter, and Klebsiella species (MICs = 3.1, 0.4, 0.8, and ≤0.2 µg/ml, respectively). Netilimicin induces nephrotoxicity in rats when administered at doses ranging from 50 to 150 mg/kg.{47387} It also induces neuromuscular block, decreasing twitch tension in isolated diaphragm and soleus muscles in rabbits (ED50s = 18.5 and 62.2 mg/kg, respectively).{47388} Formulations containing netilimicin were previously used in the intravenous treatment of severe bacterial infections.  

 

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SKU: 26666 - 10 mg Category:

Description

An aminoglycoside antibiotic; active against S. aureus, N. gonorrhoeae, E. coli, P. mirabilis, and P. aeruginosa (MICs = 0.4, 3.1, 0.8, 1.6, and 0.4 µg/ml, respectively) as well as Enterococci, Enterobacter, Citrobacter, and Klebsiella species (MICs = 3.1, 0.4, 0.8, and ≤0.2 µg/ml, respectively); induces nephrotoxicity in rats at 50-150 mg/kg; induces neuromuscular block in isolated diaphragm and soleus muscles in rabbits (ED50s = 18.5 and 62.2 mg/kg, respectively)

Formal name: O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-N1-ethyl-D-streptamine, sulfate (2:5)

Synonyms:  Netillin|Netilyn

Molecular weight: 720.8

CAS: 56391-57-2

Purity:

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Aminoglycosides||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|STDs

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