A fluorogenic substrate for trypsin-like activity of the 26S proteasome or 20S proteolytic core; upon enzymatic cleavage

Boc-LRR-AMC – 5 mg

Brand:
Cayman
CAS:
109358-46-5
Storage:
-20
UN-No:
Non-Hazardous - /

Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core.{41518,42816} Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.  

 

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SKU: 26642 - 5 mg Category:

Description

A fluorogenic substrate for trypsin-like activity of the 26S proteasome or 20S proteolytic core; upon enzymatic cleavage, AMC is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity; ex/em = 340-360/440-460 nm, respectively,

Formal name: N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide

Synonyms:  Boc-Leu-Arg-Arg-7-amido-4-Methylcoumarin|Boc-Leu-Arg-Arg-AMC

Molecular weight: 700.8

CAS: 109358-46-5

Purity: ≥98%

Formulation: A crystalline solid

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System

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