Ac-WLA-AMC – 1 mg

Brand:
Cayman
CAS:
1104011-59-7
Storage:
-20
UN-No:
Non-Hazardous - /

Ac-WLA-AMC is a fluorogenic substrate for the β5c subunit of the 20S proteasome.{42571} Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β5c subunit of the 20S proteasome. AMC displays excitation/emission maxima of 351/430 nm, respectively.  

 

Available on backorder

SKU: 26639 - 1 mg Category:

Description

A fluorogenic substrate for β5c subunit of the 20S proteasome; AMC is released upon enzymatic cleavage by the β5c subunit of the 20S proteasome and its fluorescence can be used to quantify enzyme activity; ex/em = 351/430 nm, respectively


Formal name: N-acetyl-L-tryptophyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alaninamide

Synonyms:  Acetyl-Trp-Leu-Ala-7-amino-4-Methylcoumarin|Ac-Trp-Leu-Ala-AMC

Molecular weight: 587.7

CAS: 1104011-59-7

Purity: ≥95%

Formulation: A solid


Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Proteolysis|Ubiquitin/Proteasome System