A cationic cholesterol derivative; has been used in liposome formation for gene transfection; a component of liposomes that bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA at lipsome:DNA ratios from 2.5:1-10:1 w/w; reduces viability of HepG2 cells by 63% when used in liposomes at 37.5 µg/ml

DMPAC-Chol – 5 mg

Brand:
Cayman
CAS:
184582-91-0
Storage:
-20
UN-No:
Non-Hazardous - /

DMPAC-Chol is a cationic cholesterol derivative that has been used in liposome formation for gene transfection.{42611} Liposomes containing DMPAC-chol bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA when used at lipsome:DNA ratios ranging from 2.5:1 to 10:1 w/w. DMPAC-Chol-containing liposomes also reduce viability of HepG2 cells by 63% when used at a concentration of 37.5 µg/ml.  

 

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SKU: 26583 - 5 mg Category:

Description

A cationic cholesterol derivative; has been used in liposome formation for gene transfection; a component of liposomes that bind to DNA in a band shift assay and protect against serum nuclease degradation of DNA at lipsome:DNA ratios from 2.5:1-10:1 w/w; reduces viability of HepG2 cells by 63% when used in liposomes at 37.5 µg/ml,

Formal name: (3β)-cholest-5-en-3-ol 3-[[3-(dimethylamino)propyl]carbamate]

Synonyms:  Chol-T

Molecular weight: 514.8

CAS: 184582-91-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Cancer|Cell Death||Research Area|Lipid Biochemistry|Sterol Lipids

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