An internal standard for the quantification of L-acetylcarnitine by GC- or LC-MS

Acetyl-L-carnitine-d3 (chloride) – 5 mg

Brand:
Cayman
CAS:
362049-62-5
Storage:
-20
UN-No:
Non-Hazardous - /

Acetyl-L-carnitine-d3 is intended for use as an internal standard for the quantification of L-acetylcarnitine (Item No. 16948) by GC- or LC-MS. Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine (Item No. 21489) that is catabolized by plasma esterases into carnitine.{27352,27356,27355} Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund’s adjuvant.{43555}  

 

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SKU: 26564 - 5 mg Category:

Description

An internal standard for the quantification of L-acetylcarnitine by GC- or LC-MS

Formal name: 2R-(acetyl-d3-oxy)-3-carboxy-N,N,N-trimethyl-1-propanaminium, monochloride

Synonyms:  ALCAR-d3|C2 Carnitine|L-Acetylcarnitine-d3

Molecular weight: 242.7

CAS: 362049-62-5

Purity: 99% deuterated forms (d1-d3)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Carnitines||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Neuroscience|Pain Research

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