A cephalosporin antibiotic; active against clinical isolates of S. aureus

Cefmenoxime (hydrochloride) – 1 g

Brand:
Cayman
CAS:
75738-58-8
Storage:
-20
UN-No:
Non-Hazardous - /

Cefmenoxime is a broad-spectrum cephalosporin antibiotic.{45158} It is active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. marcescens, and E. cloacae in vitro (MICs = 0.013-6.25 μg/ml). It is active against various Gram-positive and Gram-negative bacterial infections in mice (ED50s = 0.016-66 mg/kg). It increases survival in a mouse model of K. pneumoniae infection with a 50% survival dose (SD50) value of 7.6 mg/kg. Cefmenoxime is curative in a mouse model of P. mirabilis urinary tract infection with curative dose (CD50) values ranging from 0.4 to 0.75 mg/kg. Formulations containing cefmenoxime have been used to treat various bacterial infections.  

 

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SKU: 26440 - 1 g Category:

Description

A cephalosporin antibiotic; active against clinical isolates of S. aureus, S. epidermidis, S. pyogenes, E. coli, K. pneumoniae, P. mirabilis, P. vulgaris, P. morganii, S. marcescens, and E. cloacae in vitro (MICs = 0.013-6.25 μg/ml); active against various Gram-positive and Gram-negative bacterial infections in mice (ED50s = 0.016-66 mg/kg); increases survival in a mouse model of K. pneumoniae infection (SD50 = 7.6 mg/kg); curative in a mouse model of P. mirabilis urinary tract infection (CD50s = 0.4-0.75 mg/kg)

Formal name: (6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, hemihydrochloride

Synonyms:  SCE-1365

Molecular weight: 529.8

CAS: 75738-58-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Cephalosporins||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases|Pneumonia

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