A triacetylated derivative of resveratrol that has diverse biological activities; inhibits the growth of LNCaP

Acetyl Resveratrol – 1 g

Brand:
Cayman
CAS:
42206-94-0
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Acetyl resveratrol is a triacetylated derivative of resveratrol that has diverse biological activities, including anticancer and antioxidant properties.{45127,45128,45129} It inhibits the growth of LNCaP, DU145, and PC3M prostate cancer cells (IC50s = 10.5, 14.2, and 26.8 μM, respectively).{45128} Acetyl resveratrol induces cytotoxicity in ALL-5 acute lymphoblastic leukemia cells (IC50 = 3.4 μM) and induces cell cycle arrest at the G1 phase when used at a concentration of 17 μM.{45127} It also increases survival in mice exposed to total body γ-irradiation when administered at a dose of 10 mg/kg prior to irradiation.{45129}  

 

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SKU: 26379 - 1 g Category:

Description

A triacetylated derivative of resveratrol that has diverse biological activities; inhibits the growth of LNCaP, DU145, and PC3M prostate cancer cells (IC50s = 10.5, 14.2, and 26.8 μM, respectively); induces cytotoxicity in ALL-5 acute lymphoblastic leukemia cells (IC50 = 3.4 μM) and induces cell cycle arrest at the G1 phase at 17 μM; increases survival in mice exposed to total body γ-irradiation at 10 mg/kg prior to irradiation

Formal name: 5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-benzenediol, 1,3-diacetate

Synonyms:  3,5,4′-Tri-O-acetylresveratrol|Resveratrol triacetate|Triacetylresveratrol

Molecular weight: 354.4

CAS: 42206-94-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|Cell Death||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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