A positive allosteric modulator of α6β3γ2 subunit-containing GABAA receptors; selectively increases GABA-induced currents in X. laevis oocytes expressing α6β3γ2 over α1β3γ2

LAU159 – 5 mg

Brand:
Cayman
CAS:
2055050-87-6
Storage:
-20
UN-No:
Non-Hazardous - /

LAU159 is a positive allosteric modulator (PAM) of α6β3γ2 subunit-containing GABAA receptors.{52055} It selectively increases GABA-induced currents in X. laevis oocytes expressing α6β3γ2 over α1β3γ2, α2β3γ2, α3β3γ2, α4β3γ2, and α5β3γ2 subunit-containing receptors at 10 μM.  

 

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SKU: 26336 - 5 mg Category:

Description

A positive allosteric modulator of α6β3γ2 subunit-containing GABAA receptors; selectively increases GABA-induced currents in X. laevis oocytes expressing α6β3γ2 over α1β3γ2, α2β3γ2, α3β3γ2, α4β3γ2, and α5β3γ2 subunit-containing receptors at 10 μM

Formal name: 8-chloro-2,5-dihydro-2-(3-methoxyphenyl)-3H-pyrazolo[4,3-c]quinolin-3-one

Synonyms: 

Molecular weight: 325.8

CAS: 2055050-87-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation||Research Area|Neuroscience

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