An sFRP-1 inhibitor (IC50 = 0.5 μM); increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 μM); increases total bone area in a murine calvarial organ culture assay at >0.1 nM

WAY-316606 – 10 mg

Brand:
Cayman
CAS:
915759-45-4
Storage:
-20
UN-No:
Non-Hazardous - /

WAY-316606 is an inhibitor of secreted frizzled-related protein 1 (sFRP-1; IC50 = 0.5 μM).{36980} It increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 μM). WAY-316606 increases total bone area in a murine calvarial organ culture assay when used at concentrations greater than 0.1 nM.{36981}  

 

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SKU: 26324 - 10 mg Category:

Description

An sFRP-1 inhibitor (IC50 = 0.5 μM); increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 μM); increases total bone area in a murine calvarial organ culture assay at >0.1 nM

Formal name: 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)-benzenesulfonamide

Synonyms: 

Molecular weight: 448.5

CAS: 915759-45-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cell Biology|Cell Signaling|Wnt Signaling||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling

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