A broad-spectrum triazole antifungal agent; inhibits the growth of clinical isolates of A. fumigatus

Isavuconazole – 100 mg

Brand:
Cayman
CAS:
241479-67-4
Storage:
-20
UN-No:
Non-Hazardous - /

Isavuconazole is a broad-spectrum triazole antifungal agent.{46134} It inhibits the growth of clinical isolates of A. fumigatus, A. terreus, A. flavus, and A. lentulus (MIC90s = 0.39, 0.39, 2, and 0.25 mg/L, respectively) as well as C. albicans, C. krusei, and C. parapsilosis (MIC50s = 0.03, 0.06, and 0.03 mg/L, respectively).{46134,46135,46136,46137} Isavuconazole also inhibits the growth of several other fungal species, including clinical isolates of C. neoformans and C. gattii (MIC90s = 0.032 and 0.125 mg/L, respectively).{46134,46136} Formulations containing isavuconazole have been used in the treatment of invasive aspergillosis and mucormycosis.  

 

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SKU: 26211 - 100 mg Category:

Description

A broad-spectrum triazole antifungal agent; inhibits the growth of clinical isolates of A. fumigatus, A. terreus, A. flavus, and A. lentulus (MIC90s = 0.39, 0.39, 2, and 0.25 mg/L, respectively) as well as C. albicans, C. krusei, and C. parapsilosis (MIC50s = 0.03, 0.06, and 0.03 mg/L, respectively); inhibits the growth of C. neoformans and C. gattii clinical isolates (MIC90s = 0.032 and 0.125 mg/L, respectively)

Formal name: 4-[2-[(1R,2R)-2-(2,5-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]-benzonitrile

Synonyms:  BAL4815|RO 0094815

Molecular weight: 437.5

CAS: 241479-67-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals|Triazoles||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Aspergillosis||Research Area|Infectious Disease|Fungal Diseases|Candidiasis

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