A derivative of paroxetine; inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM); inhibits 5-HT uptake in rat brain synaptosomes (IC50 = 22 nM); has been used as a precursor in the synthesis of paroxetine; a potential impurity in commercial preparations of paroxetine

N-methyl Paroxetine – 1 g

Brand:
Cayman
CAS:
110429-36-2
Storage:
-20
UN-No:
Non-Hazardous - 2811 / 6.1

N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine (Item No. 14998) that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM).{48143} It inhibits serotonin (5-HT; Item No. 14332) uptake in rat brain synaptosomes with an IC50 value of 22 nM.{48144} N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine.{48145}  

 

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SKU: 26160 - 1 g Category:

Description

A derivative of paroxetine; inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM); inhibits 5-HT uptake in rat brain synaptosomes (IC50 = 22 nM); has been used as a precursor in the synthesis of paroxetine; a potential impurity in commercial preparations of paroxetine

Formal name: (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methyl-piperidine

Synonyms:  Paroxetine-Related Compound F

Molecular weight: 343.4

CAS: 110429-36-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Neuroscience|Behavioral Neuroscience|Depression

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