A reversible antagonist of P2Y12 (Ki = 23 nM); inhibits platelet aggregation in an hPRP assay (IC50 = 2.81 nM); inhibits thrombosis in a mouse model of vascular injury induced by FeCl3 at 60 mg/kg

Elinogrel – 5 mg

Brand:
Cayman
CAS:
936500-94-6
Storage:
-20
UN-No:
Non-Hazardous - /

Elinogrel is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 23 nM) that inhibits platelet aggregation in a human platelet-rich plasma (hPRP) assay (IC50 = 2.81 nM).{25099} It inhibits thrombosis in a mouse model of vascular injury induced by iron (III) chloride (FeCl3) when administered at a dose of 60 mg/kg.{45029}  

 

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SKU: 25976 - 5 mg Category:

Description

A reversible antagonist of P2Y12 (Ki = 23 nM); inhibits platelet aggregation in an hPRP assay (IC50 = 2.81 nM); inhibits thrombosis in a mouse model of vascular injury induced by FeCl3 at 60 mg/kg

Formal name: 5-chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide

Synonyms:  PRT060128|PRT128

Molecular weight: 523.9

CAS: 936500-94-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis

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