A mixture of lysophosphatidylethanolamines isolated from egg; can be generated via deacylation of phosphatidylethanolamine by PLA2; increases the phosphorylation of ERK1/2 in PC12 cells

Lysophosphatidylethanolamines (egg) – 5 mg

Brand:
Cayman
CAS:
97281-40-8
Storage:
-20
UN-No:
Non-Hazardous - /

Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2).{46055,46056} It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (Item No. 70970) and PD 98059 (Item No. 10006726) and the EGFR inhibitor AG-1478 (Item No. 10010244).{46055} LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.{46057} Lysophosphatidylethanolamines (egg) is a mixture of lysophosphatidylethanolamines isolated from chicken egg with fatty acyl groups of variable lengths at the sn-1 position and a hydroxy group at the sn-2 position.  

 

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SKU: 25844 - 5 mg Category:

Description

A mixture of lysophosphatidylethanolamines isolated from egg; can be generated via deacylation of phosphatidylethanolamine by PLA2; increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 and PD 98059 and the EGFR inhibitor AG-1478; increases neurite outgrowth and expression of neurofilament M in PC12 cells; inhibits the activity of PLD partially purified from cabbage

Formal name:

Synonyms:  Egg Lyso PE|LPE (egg)|L-α-lysophosphatidylethanolamine

Molecular weight: 0

CAS: 97281-40-8

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Glycerophospholipids||Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases||Research Area|Neuroscience

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