A sesquiterpene alcohol; inhibits the growth of L. sulphureus

(+)-Cedrol – 250 mg

Brand:
Cayman
CAS:
77-53-2
Storage:
-20
UN-No:
Non-Hazardous - /

(+)-Cedrol is a sesquiterpene alcohol that has been used in Cannabis testing and has diverse biological activities.{42271} It inhibits the growth of L. sulphureus, G. trabeum, L. betulina, and T. versicolor wood decay fungi when used at a concentration of 100 μg/ml.{36905} (+)-Cedrol inhibits the cytochrome P450 (CYP) isoforms CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 μM, respectively).{36906} In vivo, (+)-cedrol (200 mg/kg) prevents hair follicle dystrophy and reduces hair loss in a mouse model of alopecia induced by cyclophosphamide (Item No. 13849).{36907} (+)-Cedrol-loaded nanostructured lipid particles reduce peritoneal mast cell degranulation, a component of the type I anaphylactic response, induced by compound 48/80 (Item No. 22173) in mice.{36908}  

 

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SKU: 25769 - 250 mg Category:

Description

A sesquiterpene alcohol; inhibits the growth of L. sulphureus, G. trabeum, L. betulina, and T. versicolor wood decay fungi at 100 μg/ml; inhibits CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 μM, respectively); prevents hair follicle dystrophy and reduces hair loss in a mouse model of cyclophosphamide-induced alopecia at 200 mg/kg; loaded nanostructured lipid particles reduce compound 48/80-induced peritoneal mast cell degranulation in mice

Formal name: (3R,3aS,6R,7R,8aS)-octahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen-6-ol

Synonyms:  α-Cedrol

Molecular weight: 222.4

CAS: 77-53-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Immunology & Inflammation|Allergy||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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