An inhibitor of DAGLβ

(R)-KT109 – 500 µg

Brand:
Cayman
CAS:
2055172-60-4
Storage:
-20
UN-No:
Non-Hazardous - /

(R)-KT109 is the (R) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 (Item No. 18933).{43435} (R)-KT109 is an inhibitor of DAGLβ (IC50 = 0.79 nM) and of DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (Item No. 10008650; IC50 = 25.12 nM). It also inhibits α/β-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 2.51 nM. (R)-KT109 is more potent at DAGLβ, DAGLα, and ABHD6 than (S)-KT109 (Item No. 25683).  

 

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SKU: 25682 - 500 µg Category:

Description

An inhibitor of DAGLβ, DAGLα, and ABHD6 (IC50s = 0.79, 25.12, and 2.51 nM, respectively); an isomer of KT109; more potent than (S)-KT109

Formal name: (4-[1,1′-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2R)-2-(phenylmethyl)-1-piperidinyl]-methanone

Synonyms: 

Molecular weight: 422.5

CAS: 2055172-60-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Glycerolipid Lipases||Research Area|Lipid Biochemistry|Endocannabinoid/Endocannabinoid-like||Research Area|Lipid Biochemistry|Glycerolipids|Lipases||Research Area|Neuroscience

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