A naturally-occurring insecticide; a mixture of the macrocyclic lactones spinosyn A and spinosyn D

Spinosad – 10 mg

Brand:
Cayman
CAS:
168316-95-8
Storage:
-20
UN-No:
De Minimis - 3077 / 9

Spinosad is a naturally-occurring insecticide found in the the soil bacterium S. spinosa.{26995} It is a mixture of the macrocyclic lactones spinosyn A (Item No. 16528) and spinosyn D (Item No. 19158), which act as agonists of insect nicotinic acetylcholinesterase receptors (nAChRs). Oral administration of spinosad induces toxicity in fruit flies including C. capitata, B. curcurbitae, and B. dorsalis (LC50s = 2.8-4.2, 4.3-5.5, and 3.1-3.3 µg/ml, respectively) but has low toxicity in vertebrates.{39930,42230,26996} It also inhibits canine P-glycoprotein (P-gp; IC50 = 0.2 µg/ml).{39931} Formulations containing spinosad have been used in the agricultural and veterinary control of insects.  

 

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SKU: 25649 - 10 mg Category:

Description

A naturally-occurring insecticide; a mixture of the macrocyclic lactones spinosyn A and spinosyn D, which act as agonists of insect nAChRs; induces toxicity in fruit flies including C. capitata, B. curcurbitae, and B. dorsalis (LC50s = 2.8-4.2, 4.3-5.5, and 3.1-3.3 µg/ml, respectively); has low toxicity in vertebrates; inhibits canine P-gp (IC50 = 0.2 µg/ml)

Formal name: spinosyn A and D (mixture)

Synonyms:  LY232105|XDE-105

Molecular weight: 1,478.00

CAS: 168316-95-8

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Ion Channel Modulation|Activators||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Pesticides|Insecticides||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Cell Biology||Research Area|Neuroscience||Research Area|Toxicology|Drug Metabolism||Research Area|Toxicology|Environmental|Agriculture

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