A muscarinic receptor antagonist; an isomer of atropine; inhibits the arterial depressor response induced by methacholine in dogs; is more effective than atropine at inhibiting EEG arousal in dogs following sciatic nerve stimulation at 0.5 and 1 mg/kg; induces convulsions in and is toxic to mice (LD50 = 95 mg/kg)

(−)-Hyoscyamine – 5 g

Brand:
Cayman
CAS:
101-31-5
Storage:
-20
UN-No:
Limited Quantity - 1544 / 6.1

(–)-Hyoscyamine is a tropane alkaloid, a muscarinic receptor antagonist, and an isomer of atropine (Item No. 12008).{43484,43485} (–)-Hyoscyamine inhibits the arterial depressor response induced by the muscarinic agonist methacholine in dogs.{43484} It is more effective than atropine at inhibiting EEG arousal in dogs following sciatic nerve stimulation when administered at doses of 0.5 and 1 mg/kg. (–)-Hyoscyamine induces convulsions in and is toxic to mice (LD50 = 95 mg/kg).{43485}  

 

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SKU: 25644 - 5 g Category:

Description

A muscarinic receptor antagonist; an isomer of atropine; inhibits the arterial depressor response induced by methacholine in dogs; is more effective than atropine at inhibiting EEG arousal in dogs following sciatic nerve stimulation at 0.5 and 1 mg/kg; induces convulsions in and is toxic to mice (LD50 = 95 mg/kg)

Formal name: (αS)-α-(hydroxymethyl)-benzeneacetic acid, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

Synonyms:  (S)-Hyoscyamine|L-Hyoscyamine

Molecular weight: 289.4

CAS: 101-31-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Pain Research||Research Area|Toxicology

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