A carbamate insecticide; an inhibitor of acetylcholinesterase; lethal to German cockroaches (LD50s = 2.45

Propoxur – 25 mg

Brand:
Cayman
CAS:
114-26-1
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Propoxur is a carbamate insecticide and an inhibitor of acetylcholinesterase.{38711} It is lethal to German cockroaches (B. germanica) with LD50 values of 2.45, 4.73, and 1.06 μg per insect for newly emerged males, newly emerged females, and 4-week-old nymphs, respectively. Propoxur induces lactate dehydrogenase (LDH) release from and inhibits the growth of flounder gill cells (IC50s = 86.59 and 89.96 μg/ml, respectively) via induction of necrosis.{39951} It also induces yolk sac and pericardial edema in zebrafish embryos when used at concentrations of 100 and 200 μg/ml. Propoxur (8.3 mg/kg) inhibits rat blood and brain cholinesterase, decreases ambulation and rearing in an open field test, and increases latency to escape foot shock after an audio stimulus in the two-way active avoidance box in rats.{39952}  

 

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SKU: 25628 - 25 mg Category:

Description

A carbamate insecticide; an inhibitor of acetylcholinesterase; lethal to German cockroaches (LD50s = 2.45, 4.73, and 1.06 μg/insect for newly emerged males, newly emerged females, and 4-week-old nymphs, respectively); induces LDH release from and inhibits the growth of flounder gill cells (IC50s = 86.59 and 89.96 μg/ml, respectively); induces yolk sac and pericardial edema in zebrafish embryos at 100 and 200 μg/ml; inhibits rat blood and brain cholinesterase, decreases ambulation and rearing in an open field test, and increases latency to escape foot shock after an audio stimulus in the two-way active avoidance box in rats at 8.3 mg/kg ,

Formal name: 2-(1-methylethoxy)-phenol 1-(N-methylcarbamate)

Synonyms:  ENT 25,671|NSC 379584

Molecular weight: 209.2

CAS: 114-26-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Pesticides|Insecticides||Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Neuroscience||Research Area|Toxicology|Environmental

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