An oxidative metabolite of cholesterol; formed via radical and non-radical oxidation of cholesterol at the 5

5β,6β-epoxy Cholestanol – 10 mg

Brand:
Cayman
CAS:
4025-59-6
Storage:
-20
UN-No:
Non-Hazardous - /

5β,6β-epoxy Cholestanol is an oxidative metabolite of cholesterol that is formed via radical and non-radical oxidation of cholesterol at the 5,6-double bond.{13448,41987} It induces release of lactate dehydrogenase (LDH) and apoptosis in macrophage-differentiated U937 cells.{39949} 5β,6β-epoxy Cholestanol has been found in human fatty streaks and advanced atherosclerotic lesions but is not present in normal aortic tissue.{39950}  

 

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SKU: 25603 - 10 mg Category:

Description

An oxidative metabolite of cholesterol; formed via radical and non-radical oxidation of cholesterol at the 5,6-double bond; induces release of LDH and apoptosis in macrophage-differentiated U937 cells; has been found in human fatty streaks and advanced atherosclerotic lesions,

Formal name: 5β,6β-epoxy-cholestan-3β-ol

Synonyms:  5β,6β-Epoxycholestan-3β-ol|5β,6β-Epoxycholesterol,|Cholesterol β-Epoxide|NSC 148940

Molecular weight: 402.7

CAS: 4025-59-6

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Lipid Biochemistry|Reactive O2/N2 Pathways||Research Area|Lipid Biochemistry|Sterol Lipids||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Toxicology|Drug Metabolism

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