A photoreactive probe for the study of sphingosine metabolism; contains a terminal clickable alkyne moiety and a photactivatable diazirine group; has been used to monitor the metabolism of sphingosine and visualize protein-lipid interaction complexes in S1PL-/- MEFs

pacSphingosine (d18:1) – 1 mg

Brand:
Cayman
CAS:
1823021-14-2
Storage:
-20
UN-No:
De Minimis - 1170 / 3

pacSphingosine (d18:1) is a photoreactive probe for the study of sphingosine metabolism.{45245} It contains a terminal clickable alkyne moiety and a photoactivatable diazirine group that allow its interaction with sphingosine binding proteins and photo-activated cross-linking of its interacting partners, respectively. pacSphingosine (d18:1) has been used to monitor the metabolism of sphingosine and visualize protein-lipid interaction complexes in S1PL-/- mouse embryonic fibroblasts (MEFs).  

 

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SKU: 25364 - 1 mg Category:

Description

A photoreactive probe for the study of sphingosine metabolism; contains a terminal clickable alkyne moiety and a photactivatable diazirine group; has been used to monitor the metabolism of sphingosine and visualize protein-lipid interaction complexes in S1PL-/- MEFs

Formal name: (2S,3R,4E)-2-amino-13-[3-(4-pentyn-1-yl)-3H-diazirin-3-yl]-4-tridecene-1,3-diol

Synonyms:  pacSph

Molecular weight: 335.5

CAS: 1823021-14-2

Purity: ≥95%

Formulation: A solution in ethanol

Application|Click Chemistry||Product Type|Biochemicals|Labeling & Detection|Reactive Probes||Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Lipid Biochemistry|Sphingolipids

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