Description
An inhibitor of TGF-βRI; inhibits TGF-β-induced SMAD phosphorylation in vitro and in vivo; exhibits antitumor activity in the 4T1-LP triple negative breast cancer orthotopic tumor model
Formal name: 4-[[4-[[1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]oxy]-2-pyridinyl]amino]-α,α-dimethyl-2-pyridinemethanol
Synonyms:
Molecular weight: 435.5
CAS: 1898283-02-7
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|Activin-like Kinases (ALKs)||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Signaling|ALK (Activin-like Kinase) Signaling
