Procyanidin C1 – 10 mg

Brand:
Cayman
CAS:
37064-30-5
Storage:
-20
UN-No:
Non-Hazardous - /

Procyanidin C1 is a polyphenol flavonoid trimer of (–)-epicatechin (Item No. 11807) that has HIV-related and antioxidant activities.{41938,41939} It activates latent HIV-1 provirus in JLR2 cells when used at concentrations ranging from 12.5 to 50 µM and increases NF-κB-dependent transcriptional activity in Jurkat T cells.{41938} Procyanidin C1 also scavenges 2,2’-diphenyl-1-picrylhydrazyl (DPPH) radicals (IC50 = 3.2 µg/ml) and inhibits the activity of α-glucosidase (IC50 = 3.8 µg/ml) and 15-lipoxygenase (15-LO; IC50 = 57.6 µg/ml).{41939} Procyanidin C1 (10 µg/ml) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells.{34660}  

 

Available on backorder

SKU: 25201 - 10 mg Category:

Description

A polyphenol flavonoid with HIV-related and antioxidant activities; activates latent HIV-1 provirus in JLR2 cells at 12.5-50 µM; scavenges DPPH radicals (IC50 = 3.2 µg/ml); inhibits α-glucosidase activity (IC50 = 3.8 µg/ml); inhibits 15-LO activity (IC50 = 57.6 µg/ml); prevents phosphorylation of ERK1/2 and the production of ROS in THP-1 cells at 10 µg/ml


Formal name: (2R,2’R,2”R,3R,3’R,3”R,4R,4’S)-2,2′,2”-tris(3,4-dihydroxyphenyl)-3,3′,3”,4,4′,4”-hexahydro-[4,8′:4′,8”-ter-2H-1-benzopyran]-3,3′,3”,5,5′,5”,7,7′,7”-nonol

Synonyms: 

Molecular weight: 866.8

CAS: 37064-30-5

Purity: ≥98%

Formulation: A crystalline solid


Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Lipoxygenases||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS||Research Area|Lipid Biochemistry|Lipoxygenase Pathways||Research Area|Lipid Biochemistry|Sphingolipids||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic