Description
A triterpenoid saponin with diverse biological activities; selectively inhibits human recombinant renin and porcine kidney renin (IC50s = 30 and 30 μg/ml, respectively) over bovine trypsin, human urinary kallikrein, and rabbit ACE at 0.1 μg/ml; inhibits mouse brain ST3GAL1 (Ki = 2.1 μM) and decreases levels of α2,3-linked sialic acid on the cell surface and decreases migration of B16/F10 mouse melanoma cells in vitro at 75 μM; dose-dependently increases viability and mRNA expression in BRL 3A immortalized rat hepatocytes subjected to alcohol-induced oxidative stress; increases the latency to enter the dark chamber in a passive avoidance test and the percentage of spontaneous alterations in the Y-maze test in an ibotenic acid-induced rat model of learning and memory impairment at 10 mg/kg per day
Formal name: (3β,4β,22β)-22,23-dihydroxyolean-12-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-β-D-glucopyranosiduronic acid
Synonyms: Soyasaponin I
Molecular weight: 943.1
CAS: 51330-27-9
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Saponins||Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity
