A non-steroid glycoside with diverse biological activities; inhibits LPS-induced ROS and NO release as well as iNOS and COX-2 protein expression in RAW 264.7 mouse macrophages at 200 μM; dose-dependently inhibits thrombin-induced human platelet aggregation in vitro and thrombin-induced DIC in rats at 100 mg/kg; increases the 20-day survival of Sendai virus-infected mice at 1 mg per day for three days prior to infection; stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth at 0.2 mg per animal topically

Ginsenoside Ro – 10 mg

Brand:
Cayman
CAS:
34367-04-9
Storage:
-20
UN-No:
Non-Hazardous - /

Ginsenoside Ro is a non-steroid glycoside that has been found in plants of the genus Panax and has anti-inflammatory, antithrombotic, and antiviral biological activities.{39882,39883,39884,39886,39887,39885} It inhibits LPS-induced release of reactive oxygen species (ROS) and nitric oxide (NO) as well as inducible nitric oxide synthase (iNOS) and COX-2 protein expression in RAW 264.7 murine macrophages when used at a concentration of 200 μM.{39883} Ginsenoside Ro dose-dependently inhibits human platelet aggregation induced by thrombin (Item No. 13188) in vitro and thrombin-induced disseminated intravascular coagulation (DIC) in rats when administered at a dose of 100 mg/kg.{39884,39886} It increases the 20-day survival of Sendai virus-infected mice when administered at a dose of 1 mg per day for three days prior to infection.{39887} Topical administration of ginsenoside Ro (0.2 mg per animal) also stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth.{39885}  

 

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SKU: 25137 - 10 mg Category:

Description

A non-steroid glycoside with diverse biological activities; inhibits LPS-induced ROS and NO release as well as iNOS and COX-2 protein expression in RAW 264.7 mouse macrophages at 200 μM; dose-dependently inhibits thrombin-induced human platelet aggregation in vitro and thrombin-induced DIC in rats at 100 mg/kg; increases the 20-day survival of Sendai virus-infected mice at 1 mg per day for three days prior to infection; stimulates hair regrowth after shaving in a mouse model of slowed hair regrowth at 0.2 mg per animal topically

Formal name: (3β)-28-(β-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranosiduronic acid

Synonyms:  Chikusetsusaponin V

Molecular weight: 957.1

CAS: 34367-04-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products|Glycosides||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Cardiovascular System|Blood|Thrombosis||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Infectious Disease|Viral Diseases|Influenza

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