A GVIA iPLA2 inhibitor; inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction; selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows less than 25% and 32.8% inhibition

GK187 – 5 mg

Brand:
Cayman
CAS:
1071001-50-7
Storage:
-20
UN-No:
- 1231 / 3

GK187 is an inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2), an enzyme involved in basal cell metabolism.{40941} It inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows less than 25% and 32.8% inhibition, respectively.  

 

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SKU: 25130 - 5 mg Category:

Description

A GVIA iPLA2 inhibitor; inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction; selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows less than 25% and 32.8% inhibition, respectively

Formal name: 1,1,1,2,2-pentafluoro-7-(4-methoxyphenyl)-3-heptanone

Synonyms: 

Molecular weight: 310.3

CAS: 1071001-50-7

Purity: ≥95%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases

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